Antioxidant action and cytotoxicity on HeLa and NIH-3T3 cells of new quercetin derivatives
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منابع مشابه
Antioxidant action and cytotoxicity on HeLa and NIH-3T3 cells of new quercetin derivatives
Quercetin is a natural polyphenol with proven health beneficial activities. In this study 15 new quercetin derivatives were prepared with the aim to enhance their bioavailability. Modification of their physicochemical properties could herewith improve the action in cells. The prepared compounds were tested for their antioxidant and cytotoxic activity. The ability to scavenge free radicals as we...
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Quercetin, a ubiquitous flavonol, represents a promising leading drug for development of new chemotherapeutic agents. However, its limited cytotoxicity to cancer cells hampers its clinical use. In order to obtain novel quercetin derivatives with superior cytotoxicity, seven alkylated quercetin derivatives were synthesized. Solubility of these derivatives was determined by turbidimetry. Cytotoxi...
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ژورنال
عنوان ژورنال: Interdisciplinary Toxicology
سال: 2013
ISSN: 1337-9569,1337-6853
DOI: 10.2478/intox-2013-0031